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There will be less risk of hospitalization with Omicron than with Delta

(CNN) – Two new, previously published articles add to the mounting evidence that the omicron variant of the coronavirus may be less likely to cause serious illness and hospitalization than the delta variant.

A study published online on Wednesday as a working paper by researchers at the University of Edinburgh in the UK suggests that Omicron is associated with a two-thirds lower risk of hospitalization due to COVID-19 compared to Delta. This search was performed in Scotland.

The other document, published Tuesday on the web server medrxiv.org, notes that people with an omicron infection were 80% less likely to be hospitalized than a delta infection. But once a patient was hospitalized, there was no difference in the risk of serious illness, according to that South African research.

Both studies include preliminary data and have not yet been published in a peer-reviewed journal.

The Scottish study included data from 23,840 omicron cases and 126,511 delta cases, from 1 November to 19 December. The researchers – from the University of Edinburgh, the University of Strathclyde and the Scottish Public Health Office – examined the health outcomes of omicron infection compared to delta infection. There were 15 hospitalizations among omicrons and 856 hospitalizations among deltas.

“Although their numbers are small, the study is good news,” said James Naismith, director of the Rosalind Institute. “The two-thirds reduction in hospitalization for young vaccinated twice as much compared to delta suggests that Omicron would be milder for more people.” Franklin and Professor of Structural Biology at Oxford University, who was not involved in either study, said in a written statement distributed by the UK Center for Science Media on Wednesday.

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“The study is rigorous, but it’s early days (so it could change a bit with more data and more studies will be reported in the coming weeks). Keep in mind that some South African scientists have long said Omicron was softer.” Naismith said. “Although a two-thirds reduction is significant, the omicron can cause serious illness in doubly vaccinated people. Therefore, if the omicron continues to double every few days, it could lead to significantly more hospitalizations than delta in the population with multiple vaccinations. They were doubly vaccinated.”

The researchers found that the proportion of oomicron cases that were potentially re-infected in people who had previously been infected with COVID-19 was more than 10 times that of delta. The data also showed that getting a third dose of the vaccine, or the booster vaccine, was associated with a 57% lower risk of developing oomicron infection symptoms when compared to at least 25 weeks after completing a second dose.

This is how the omicron variant of the new coronavirus affects the world 7:35

“This first national data indicates that Omicron is associated with a two-thirds reduction in the risk of hospitalization for COVID-19 compared to Delta. Although it provides the greatest protection against Delta, the third booster dose of vaccination provides additional protection,” the researchers wrote in the paper. The symptomatic infection with the COVID-19 virus is the omicron.

The other work used data on 161,328 cases of COVID-19 reported nationally in South Africa between October 1 and December 6. The researchers – from the National Institute of Infectious Diseases, the University of the Witwatersrand and the University of Cape Town – found that among people with oomicron, 2.5% were hospitalized during that time, compared with 12.8% of people infected. with delta.

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“This is early data and results may change as the epidemic progresses,” the researchers wrote in their paper.

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